If you are trying to secure some Ozempic for yourself, you better make sure you aren’t buying fake GLP-1 drugs. High prices and market shortages make certain websites very appealing to consumers, but counterfeit drugs can pose serious health risks. How can you know what’s in these fake drugs? Should you want to start using Ozempic, make sure to verify the legitimacy of any only pharmacy you use. 

GLP-1 drugs, like Ozempic, increase insulin sensitivity and stimulate insulin secretion. These drugs also reduce blood sugar in people with type 2 diabetes. Because they can make you feel full, they have become a popular drug to promote weight loss, especially amongst overweight or obese people. Unfortunately, GLP-1 drugs can be very expensive without insurance. One carton of Ozempic, for example, can cost about $1,000 at U.S. pharmacies. 

All of these factors create opportunities for people to sell fake prescription drugs, ultimately taking advantage of consumers. One report found that social media websites were popular spaces for promoting fake drugs. Of the 3,968 fake listings removed in 2023, almost 60% were found on Facebook. Some experts believe that these fake sites target Facebook because the users tend to be a little older and less likely to spot a scam. 

Why Are Fake Drug Websites So Dangerous?

Registered dietitians have given remarks about the recent emergence of fake GLP-1 drugs. They say that the biggest danger with buying from fake drug websites is that you don’t know what you are getting. You take a big risk when you take an unregulated drug because it could contain anything. What’s the best case scenario? You get an inert placebo. On the other side of the coin, you could put something incredibly dangerous in your body. 

One of the major risks with taking these fake drugs is that they could be laced with heavy metals and other harmful toxins. Hundreds of ER visits every year are due to severe allergic reactions or lead poisoning, which people acquired from unknown sources. The Food and Drug Administration (FDA) also indicates that because most GLP-1 drugs are injected, the risk of infection is high, considering the sterility of needles can’t be confirmed. Novo Nordisk, the manufacturer of Ozempic, notes that you cannot confirm the efficacy of fake medications. That could be very dangerous for people who use these meds to control blood sugar. 

How To Know If You Are Buying Fake Medications

The language on the sites selling fake medications is typically the same copy on real online pharmacies. Fake sites use deceptive tactics to not only appear genuine, but also to fool consumers. In fact, some sites will copy the branding and logos of reputable pharmaceutical companies. The discounted price is a big factor that tends to entice consumers who don’t want to pay the full price tag. It’s like looking for an item on a website and then looking somewhere else for the knock-off version. If you want to determine the legitimacy of the medication, consider the following: 

• Beware of suspiciously low prices: Super discounts could mean that the product is expired or counterfeit.
• Use reputable online pharmacies: Make sure that the contact information is verified and that the payment methods are secure. Additionally, look for accreditation from authorities. 
• Look for accreditation: Verified seals or certifications can indicate credible websites. The National Association of Boards of Pharmacy provides a database of credible pharmacies. 
• Verify the credentials: Before you make the purchase, make sure that the pharmacy has an active license in the state where it dispenses the medications. If it looks suspicious or you don’t have a good feeling about it, abort the mission. 
• Check the authenticity of the medication: Make sure to research the appearance of the medication, how it’s packaged, and the manufacturer before you order or use it. Compare what you are looking at with the real medication. Novo Nordisk, for example, may offer real and fake photos to help you discern the real meds from the fake ones.

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In Japanese, maitake literally translates to dancing mushroom. Legend has it that this beneficial mushroom received its name because people danced with happiness after finding it in the wild. Maitakes are adaptogens that exhibit impressive healing properties. Researchers note that adaptogens help the body fight mental or physical difficulties, regulating systems in the body that are out of balance. 

What Are Maitake Mushrooms?

These edible mushrooms are native to China, but they also grow in Japan, Europe, North America, and other parts of Asia. You may also know maitake mushrooms as hen of the woods or sheep’s head mushrooms. They exhibit a tasty umami flavor, making it a sought after culinary ingredient, but they also offer an impressive nutritional profile. Maitakes are naturally rich in antioxidants, beta-glucans, potassium, fiber, vitamins B, C, and D, copper, amino acids, and other minerals. They are also low-calorie, low-sodium, fat-free, and cholesterol-free. 

Maitake mushrooms are of great interest to scientists because of their unique antioxidant profile. Existing research points to the fact that these mushrooms have a unique way of supporting overall health and fighting certain illnesses. They have many bioactive compounds, which likely contribute to their many medicinal properties. Continue reading to learn more about the health benefits of maitake mushrooms. 

They Provide Cancer Support

According to research, the beta-glucans in maitake mushrooms have an anti-tumor immune response. Some scientific studies on mice found that maitakes blocked tumor growth. Additional research found that beta-glucans potentially enhanced the activity of certain immune cells, including natural killer (NK) cells and macrophages. These cells help to identify and destroy cancer cells. Maitake mushrooms also promote apoptosis, which is programmed cell death that eliminates abnormal (cancerous) or damaged cells. Some studies suggest that maitake mushroom extracts may induce apoptosis in breast cancer and bladder cancer cells. One such extract, which is available in supplement form, is maitake D-fraction. Vitamin C helps to enhance this extract’s function to make it more effective in the body. 

They May Support Healthy Blood Sugar

A study from 2015 found that maitake mushrooms had a positive effect on rats with type 2 diabetes. Over the course of the study, the rats consumed maitake mushrooms, which had a positive effect on blood glucose levels. Study authors were able to conclude that the bioactive compounds in maitake mushrooms helped improve glucose tolerance. A separate study on diabetic mice found that maitake mushroom powder exhibited anti-diabetic properties, improving the condition of the mice over four months. Human research is necessary, but initial studies on animals are promising. 

They Promote Fertility

Before we explain how maitake mushrooms promote fertility, it’s crucial to understand that research is limited. Additionally, the research was specifically focused on how they affected women with polycystic ovarian syndrome (PCOS). This is a condition that causes the ovaries to develop fluid-filled cysts around their outer edges. These cysts contain follicles, but don’t release eggs, resulting in infrequent periods, excess hair growth, and lack of ovulation. A Japanese study from 2010 monitored women with PCOS who either took a maitake mushroom extract or the clomiphene citrate drug. At the end of the study, the maitake extract induced ovulation in 77% of PCOS participants, showing a very similar result to the prescription drug. 

They May Reduce Blood Pressure

Earlier in the article, we discussed the D-fraction maitake extract, which can induce apoptosis. In an animal study, researchers gave that D-fraction extract to rats and found that it reduced age-related high blood pressure. The extract also improved insulin sensitivity, which could help explain why maitake can aid with cholesterol reduction. In an older study from 1989, researchers fed maitake mushrooms to rats for eight weeks. At the end of the study, the rats had lower blood pressure, triglyceride, and cholesterol levels. The ability to lower all of these markers suggests that maitake mushrooms may be able to reduce the risk of metabolic syndrome and heart disease. 

They Support Immune Function

The beta-glucans in maitake mushrooms work to encourage optimal immune function. The polysaccharides work to optimize immune response, enhancing the body’s overall resilience towards foreign invaders. The bioactive polysaccharides support humoral and cellular immunity, two actions that ward off pathogens. This is particularly useful whether a virus is going around the office, or you are stressed and have a weakened immune system. When compared to shiitake mushrooms in a 2014 animal study, maitake mushrooms stimulated a more intense immune response. 

They May Balance Cholesterol Levels

If you have higher levels of low-density lipoprotein (LDL) cholesterol, you have a higher risk of heart disease. Although high cholesterol can result from poor diet and genetics, health experts suggest that insulin resistance plays a role in cholesterol levels. As it turns out, the antioxidants in maitake mushrooms work to reduce oxidative stress and inflammation. When inflammatory markers reduce, less cholesterol accumulates in the arteries. That ultimately helps protect you from heart disease.

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It’s no secret that new weight loss drugs are highly sought after in the United States. The reason for that is because they are highly effective, so long as you continue using them. Ozempic, Wegovy, Zepbound, Mounjaro, and other similar medications work by recreating the effects of GLP-1, a hormone that the gut produces once you finish eating. This hormone reduces both hunger and cravings, helping you to eat less, which promotes weight loss. 

What happens when you stop taking these medications, though? Recent research suggests that you can regain weight once you stop taking them. Health experts have started to refer to this weight gain as “Mounjaro plateau” or “Ozempic rebound.”

Why Do People Stop Using These Medications?

People stop taking these medications for numerous reasons, with a common one being the high cost, which is especially true for people without health insurance. Even if you have health insurance, many providers don’t offer coverage for these drugs. There is a huge demand, supply issues, and many unwanted side effects that come from using these medications. In fact, clinical trials found that up to 10% of users stop using these medications because of side effects, including nausea and disruptive bowel movements. 

It’s possible that the number of people who stop using these medications is higher than that 10% figure. Patients may have less aftercare, support, and accountability than they do in clinical trials. That means there is most likely a higher percentage of people who experience unwanted side effects, which could be easily managed. Doctors also state that people stop using these medications once they meet their goal weight. 

Why Do You Gain Weight Post-Medication?

Ozempic, and other related drugs, were originally intended to help people with type 2 diabetes manage blood sugar levels. During clinical trials, researchers observed weight loss to be a surprising side effect. That got them thinking, so they started to prescribe these medications for weight loss (an off-label purpose). 

In present day, many people with high blood pressure, type 2 diabetes, high cholesterol, or fatty liver disease, have been struggling to lose weight for 20 to 30 years. Drugs like Ozempic or Wegovy help people lose weight by temporarily altering hunger mechanisms. Basically, they provide a synthetic form of GLP-1, which is the hormone that helps you feel satiated and less hungry. At the same time, these drugs also promote an increase in insulin response to food, which works to regulate blood sugar. They also reduce the release of glucagon, a hormone that opposes insulin and tends to increase blood glucose levels. 

When you stop taking these medications, the body naturally produces more ghrelin, the hunger hormone. Once off the medications, the body’s metabolic rate slows down. The combination of a slower metabolic rate and a rapid onset of hunger causes weight gain, especially if there is no modification in lifestyle or diet. 

How Common Is Weight Gain After Stopping Ozempic?

If you use Ozempic to lose weight, the last thing you want is to see the weight return once you stop taking the drug. As it turns out, it is very common for a person to gain weight after quitting Ozempic or similar medication. One study found that people who stopped taking semaglutide (the active ingredient in Ozempic) and quit lifestyle interventions gained two-thirds of their weight back within a year. Another study monitored people who stopped taking tirzepatide, the active ingredient in Zepbound and Mounjaro. Within one year of quitting the drug, they gained more than half the weight they’d lost while on the drug. 

The Takeaway

Before you take any GLP-1 agonist (such as Ozempic), consult your healthcare professional and make sure you understand the risks. Are you using the drug for short-term or long-term results? If you decide to take Ozempic, make sure you understand what will happen once you stop. Your healthcare professional may be able to provide guidance, nutritional advice, and an exercise regimen to help stave off the weight you lost while on the drug.

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Berberine is a naturally occurring compound in many plants. For thousands of years, it has been used in Traditional Chinese Medicine (TCM), Ayurveda, and other medicinal traditions to treat digestive disorders, inflammatory conditions, and infections. Some research indicates that it may offer protection against high blood pressure, diabetes, and high cholesterol, among other conditions. 

What Is Berberine?

Extracted from several plants, berberine is a bioactive compound that belongs to the alkaloid class. It is yellow and typically used as a dye, despite its long history in traditional medicinal applications. Modern evidence suggests that it exhibits impressive health benefits that may address chronic conditions. As of now, limited human research indicates that berberine may lower cholesterol, triglycerides, and blood sugar levels. This is of great interest to the health experts because these are reversible risk factors for heart disease. Although it appears to be safe and only causes a few mild side effects, you may want to consult a healthcare professional if you are interested in taking it. 

How Does Berberine Work?

There have been hundreds of studies on berberine’s effects on the body. According to animal studies, one of berberine’s primary actions is to activate AMP-activated protein kinase (AMPK), an enzyme inside cells. Found in cells throughout the body, AMPK has an active role in regulating metabolism and energy levels. Berberine also has an effect on other molecules inside cells, potentially affecting which genes are turned on or off. That may help protect against many chronic health conditions, but more research is necessary on this matter. Continue reading to learn more about berberine’s health benefits. 

May Protect Against Bacterial Infections

A 2022 study found that berberine helped prevent the growth of Staphylococcus aureus. Researchers note that this bacterial strain can cause sepsis, pneumonia, meningitis, and a range of skin conditions. Another study found that berberine exhibited an ability to damage the DNA and protein of certain bacteria, due to its antimicrobial activity. 

It Helps Lower Blood Sugar Levels

According to many studies, berberine can significantly lower blood sugar levels in people with type 2 diabetes. In 2008, study authors monitored a group of 116 participants who took one gram of berberine per day. The results indicated that berberine lowered fasting blood sugar by 20%, and it also lowered hemoglobin A1c (HbA1c) by 12%. Additionally, berberine improved blood lipids, including cholesterol and triglycerides. Researchers note that berberine seems to work in several ways to aid these processes:

• Decreases sugar production in the liver
• Reduces insulin resistance to make insulin more effective
• Increases the amount of beneficial bacteria in the gut
• Slows the breakdown of carbohydrates in the gut
• Increases glycolysis, which helps the body break down sugars inside cells

May Aid Weight Loss

There is a lot of attention on berberine because it may be a viable weight loss supplement. An older 12-week study involved people with obesity who took 500 milligrams (mg) of berberine three times daily. At the end of the study, participants experienced five pounds of weight loss, on average, with a 3.6% reduction in body fat. A review of 12 studies noted that supplementing with berberine led to significant reductionist body weight, belly fat, and body mass index. It was also effective at decreasing C-reactive protein, a marker of inflammation. Other research found that berberine works to inhibit the growth of fat cells at a molecular level, which may promote weight loss. Although existing research is promising, more research is necessary to determine berberine’s weight loss effects.

It Helps Lower Cholesterol

If you have high levels of triglycerides and LDL cholesterol, you have a higher risk of heart disease and stroke. Some research suggests that berberine may help lower LDL cholesterol and triglyceride levels. One review of both animal and human studies found that berberine exhibits cholesterol lowering effects. Researchers believe that berberine’s effects are similar to drugs that reduce high cholesterol. The only difference is that berberine does not cause the same side effects. 

May Benefit People With Obesity

There is an obesity epidemic in the United States, and it increases a person’s risk of type 2 diabetes, heart disease, high cholesterol, and high blood pressure. One review found that people who took 750 mg of berberine twice daily for three months experienced significant weight loss. Another double-blind study monitored people with metabolic syndrome who took 200 mg of berberine three times daily. Participants experience decreases in their body mass index scores. Finally, some research suggests that berberine works similarly to metformin, a drug that doctors typically prescribe people with type 2 diabetes. Additionally, berberine works to alter gut bacteria, which may benefit people with diabetes and obesity.

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As you enter your 40s, the body starts to lose muscle tissue gradually, also known as sarcopenia. Since muscle burns more calories than fat does, losing muscle mass means that your metabolism slows down. That’s not the only hurdle that you face, though. For those who are assigned female at birth, the transition through menopause (perimenopause) is the second hurdle in the way of your weight loss efforts. 

Losing weight in your 40s just isn’t as easy as it was when you were in your 20s and 30s. Plus, it is more common for people to gain fat in this stage of life, especially around the midsection. Additionally, blood sugar levels may increase, which doesn’t make weight loss any easier. So how do you lose weight, or even maintain weight, during your 40s? Hopefully, the following tips aid your weight loss efforts. 

Prioritize Protein

If you want to lose weight, dietitians encourage higher protein consumption because it is more filling than carbohydrates. Eating protein may help you eat less later in the day, whereas carb-centric foods can cause late night cravings. A 2015 study found that menopausal women who ate higher amounts of protein weighed less and had less body fat than people who ate less protein. Higher protein eaters ate 0.8 grams of protein per kilogram of body weight per day. That equates to 55 grams of protein for a person who weighs 150 pounds. Great sources of protein to include in your diet are Greek yogurt, peanut butter, almond butter, organic eggs, kidney beans, black beans, cannellini beans, and wild caught fish. 

Keep Stress Levels Down

Easier said than done, right? As you know, there are new demands sandwiched between adulting, raising kids, and everything else that comes with life in your 40s. Keeping stress levels in check can aid your weight loss efforts. When you are stressed, your cortisol levels are much higher, and they elevate blood sugar and encourage weight gain, especially in the midsection. When you keep your stress in check, you may find that cravings disappear and you have an easier time eating healthier foods. Before you manage stress, identify what your stressors are, so that you know what is in your control. You can control your thoughts and beliefs, not the weather or economic uncertainty. Meditation, exercise, massage, deep breathing, Tai Chi, and yoga are all great stress-relieving practices. 

Establish Your Caloric Needs

There is a difference between eating the average caloric intake and eating the calories your body actually needs. More often than not, people eat more calories than their bodies require. Caloric needs change as you age, so you usually need fewer calories than you did in your 20s and 30s to fill you up. Your caloric needs will vary depending upon your age and your activity level. For example, a 40-year-old sedentary person requires fewer calories than the same person who is moderately active. That same moderately active person needs fewer calories than a highly active person. Moderately active means you walk between one-and-a-half and three miles daily, with active being anything more than that. If you want to lose weight, subtract about 500-750 calories from your weight-maintenance number, but don’t fall below 1,500 calories per day. 

Consider Changing Up Your Exercise Routine

If you regularly work out and don’t see that the number on the scale reflects your efforts, you may need to change up your routine. It’s possible that both your muscle mass and bone density decrease. Another factor is a shift in hormones, which leads to abdominal weight gain. The type of activity you do can influence your results. Strength training can help you maintain muscle and offset bone density loss. If you want to target belly fat, high-intensity interval training is usually your best bet. Just don’t choose weight-bearing exercises that put too much stress on the body. You want to complement your stress-relieving efforts with yoga, for example. If you know how to manage your stress, consider adding more high-intensity workouts per week. 

Eat Fewer Carbs

This is something that nobody wants to hear because carbs are just that good. Lowering your carb intake may help prevent weight gain and make weight loss easier, though. Carbs can throw off your hormones, and you want your sex hormones and insulin in check if you want to lose weight. Sex hormones work with insulin to regulate blood sugar levels. If these hormones are out of whack, you have a higher risk of insulin resistance. Cut back on carbs, especially if you are perimenopausal, to encourage weight loss. If you are going to eat carbs, focus on complex carbs in foods like fruits, vegetables, legumes, and whole grains.

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Isn’t it amazing when you get to wake up a little later on a Saturday morning? The sun peaks through your curtains/blinds and helps you wake up when you enter the rest of your house. Basking in the glow of morning sunshine helps to boost your mood and provide natural energy. Maybe you sip some morning tea or lemon water and pop a squat on your couch while doing so. The only other thing that can enhance a morning such as this is a refreshing and nourishing cucumber grapefruit juice.

Juice is so easy to make, even if you don’t have a juicer. As a quick note for people who want to make juice without juicers, blend your ingredients in a blender and then pour the blended mixture through a fine mesh sieve, pressing the pulp to extract as much liquid as possible. You may end up with some bits and pieces in your juice, but the flavor is there and that’s what matters! Just keep in mind that your blended mixture will not yield as much juice as is in the blender. This is because you remove the fiber from the ingredients, which is leftover in the pulp.

This cucumber grapefruit juice is low in calories and incredibly refreshing. The spicy kick from the ginger adds a little zing that wakes up your palate. Both cucumber and grapefruit have a water content that exceeds 90%, so they aid your hydration efforts. Grapefruit is rich in vitamin C, which aids immune function, and it may help prevent insulin resistance, which can lead to diabetes. Studies suggest that eating grapefruit can help regulate blood sugar levels and keep insulin levels controlled. How amazing is that?!

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Research shows that aloe vera juice may be beneficial for people with diabetes. Aloe vera contains active components that help in lowering high blood pressure. It’s also been shown to lower blood glucose levels. Please consult with a doctor before consuming.

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Diabetes can damage nerves and cause complications. This is known as neuropathy and symptoms usually begin with the loss of sensation in the toes, and possibly fingers. Treatment includes managing blood sugars.

Chapters:
0:00 Intro
0:43 Diabetes makes your skin weaker and that’s why you get more cuts and sores.
2:18 Tingling or pins and needles in the hands and feet is only from letting them fall asleep.
3:17 Diabetic nerve damage can get bad enough that you don’t notice the gangrene.
6:04 The nerve damage is the only reason cuts on diabetic feet don’t heal.
7:22 Outro

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Gestational diabetes develops when the body cannot produce the insulin it needs during pregnancy, because of the higher levels of hormones. It usually goes away after birth, but if it doesn’t it then becomes type 2 diabetes.

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Some studies suggest bitter melon can help lower blood sugar in people with type 2 diabetes. It also contains vitamins A and C, as well as iron. Consider adding it to your meals as a healthy addition to your diet.

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